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Covid-19 Vaccine

FROM THE ARCHIVES

As the world gears up for the fastest-ever developed vaccine, several drug companies have taken different routes to manufacture the antidote to the pandemic that has held the world hostage since March of this year.

According to the Johns Hopkins Coronavirus Resource Center, at least 1.3 million people have died as a result of and at least 59 million people have been infected with COVID-19 worldwide.

With the global economy at stake, millions working from home and, according to UNICEF, 463 million children around the world unable to access remote learning, the need for a vaccine is urgent.

A government-appointed panel of experts has approved a coronavirus vaccine developed by AstraZeneca and Oxford University for emergency use and will send its recommendations to the country’s drugs regulator, the Drugs Controller General of India
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This duo spent more than a decade cracking a complex viral puzzle—and their skills were needed once more. Their years of sleuthing and innovating ultimately contributed a microscopic but critical piece to the most promising candidates for COVID-19 vaccines. Two already authorized in the U.S. use their discovery, as do
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The World Health Organization has listed Pfizer-BioNTech’s COVID-19 vaccine for emergency use, a critical step that the United Nations health agency said aims to make the vaccine more readily available in developing nations.
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In what has become a familiar pattern, the COVID-19 vaccine landscape has changed overnight, simultaneously raising hopes that more people may soon get vaccinated and triggering confusion. “It’s crazy,” says immunologist John Moore, a vaccine researcher at Weill Cornell Medicine. “Every morning, it’s just, ‘What’s going on?’"
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A vaccine developed by China National Pharmaceutical Group (Sinopharm) has been found to be 79.34 per cent effective against Covid-19, according to an interim analysis, the company said.
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Our fundamental comprehension of immune responses to the coronavirus has grown significantly, but more questions—like the longevity of immunity—are still to be answered, especially amid concerns that mutations may help SARS-CoV-2 evade our immunological defenses.
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Like the Pfizer vaccine, the Moderna vaccine primes the immune system to attack the coronavirus that causes COVID-19 by delivering a snippet of the virus’s genetic code. That code — known as messenger RNA, or mRNA — instructs the body to build copies of the spike protein that studs the
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Shanghai Fosun Pharmaceutical Group Co Ltd on Wednesday said it will buy at least 100 million doses of a COVID-19 vaccine from Germany’s BioNTech SE for use in mainland China next year, if the vaccine receives approval.
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As more Covid-19 vaccines approach the finish line of regulatory approvals, the next challenge will be to produce and deliver hundreds of millions of doses as quickly as possible.
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"Higher income countries like the U.S. and the U.K. are putting themselves at the front of the line — that's obviously what's happening," Philip Clarke, a professor of health economics at the University of Oxford, said. "The clear failure here is not having stronger international institutions and stronger funding to
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Residents of two long-term care homes in Quebec will be the first to receive the Pfizer-BioNTech vaccine in that province. Francine Dupuis of the Montreal regional health agency says health care workers have been ready to administer the doses at Maimonides Geriatric Centre since Friday.
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Analysis of contracts countries are signing with vaccine makers for advance booking of candidates shows that the deals are still fluid, changing in a matter of days with some companies gaining and some losing orders given that most candidates are still in trial stage.
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Singapore has approved Pfizer-BioNTech's novel coronavirus vaccine and expects delivery of the first shots by the end of December, Prime Minister Lee Hsien Loong said on Monday. The city-state of 5.7 million people expects to have enough vaccines for everyone by the third quarter of 2021 and will make it
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Bahrain said Sunday it approved the use of a Chinese coronavirus vaccine, following its earlier approval of a vaccine made by Pfizer and its German partner BioNTech.
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Hospital systems nationwide should expect the first shipments of Pfizer's Covid-19 vaccine to arrive Monday, Gen. Gustave Perna, chief operating officer of Operation Warp Speed, said during a media briefing Saturday.
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The United States became the third highly developed Western country — after Britain and Canada — to approve the vaccine. But the three countries have very different health care systems. And they face different challenges in the race to get the vaccine to millions of people.
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The Hong Kong government weighed scientific, logistical, business and even political factors before choosing the manufacturers to supply millions of Covid-19 vaccine shots to the city’s residents, according to health experts and an insider close to the selection process.
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As the race to develop a COVID-19 vaccine concludes, a new one begins: the race to ensure that enough people are vaccinated to end the pandemic.
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Pfizer Inc. is packing boxes with thousands of its Covid-19 vaccines for shipment around the U.S., as hospitals gear up to give shots while also confronting the surging pandemic. Trucks carrying the fragile cargo at minus-94 degrees Fahrenheit will start rolling out of Pfizer plants in Michigan and Wisconsin on
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Africa Centers for Disease Control and Prevention Director John Nkengasong warned “it will be extremely terrible to see” wealthy nations obtaining vaccines and African countries missing out, as he called on for an extraordinary United Nations session to discuss this “moral issue” and avoid a “North-South distrust in respect to
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The scientists and the World Health Organisation (WHO) tell us the Covid-19 vaccines have been produced in an unprecedented spirit of worldwide co-operation. Scientists across many disciplines have shared information and these vaccines have arrived long before it would have been thought possible a year ago.
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The Food and Drug Administration has authorized the use of a COVID-19 vaccine developed by Pfizer and BioNTech, a landmark moment in the fight to suppress a virus that has killed nearly 300,000 people in the United States and sickened tens of millions around the world.
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Hong Kong has secured 15 million shots of Covid-19 vaccines manufactured in China and Europe, with the first million expected to be available next month for high-risk groups under a free, voluntary vaccination scheme for the city’s population of 7.5 million residents.
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France's Sanofi and Britain's GSK said Friday their Covid-19 vaccines will not be ready until the end of 2021, after interim results showed a low immune response in older adults. The announcement is a huge setback in efforts to fight the pandemic, which emerged in China last December and has
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The world is watching as the UK becomes the first test case of our collective ability to manufacture, ship, and deliver an entirely new class of vaccines, on a scale and speed that no previous vaccination drive in history has ever approached.
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Pharmaceutical and vaccine production involves complex coordination, involving product development, manufacturing, packaging, storage, distribution, and regulatory review, and each stage can cause unexpected delays.
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Development of a COVID-19 vaccine in Australia was abandoned Friday, December 11, after clinical trials produced a false positive HIV result among subjects involved in early-stage testing.
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Documents released by US regulators on Tuesday confirmed that Pfizer and BioNTech’s Covid-19 vaccine was strongly protective against the disease – offering the world’s first detailed look at the evidence behind the shots.
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Many Asian countries have signed agreements with vaccine makers for supply. India has secured 600 million doses, mostly from AstraZeneca, according to data from Airfinity, a science information and analytics company. China, Japan, Indonesia, South Korea and Thailand all have deals for millions of doses from the European company.
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Three vaccine companies have applied for early approval for emergency use in India: Serum Institute of India, which has been licensed to manufacture the AstraZeneca vaccine, Pfizer Inc and Indian manufacturer Bharat Biotech. “Some of them may get licensed in the next few weeks,” federal Health Secretary Rajesh Bhushan said.
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The Covid-19 vaccine being developed by the University of Oxford and AstraZeneca appears to have moderate efficacy in preventing symptomatic illness, and may significantly reduce hospitalization from the disease, data from four clinical trials of the vaccine reveal.
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A recent study has created a novel test using an ultrasensitive paper-based electrochemical sensor that can rapidly detect the presence of the virus in 5 minutes or less.
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An experimental coronavirus vaccine developed by China National Pharmaceutical Group (Sinopharm) has 86% efficacy, the health ministry of the United Arab Emirates said on Wednesday, citing an interim analysis of late-stage clinical trials.
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South Korea has ordered COVID-19 vaccines for 88 percent of its population, or 44 million people, the government said, announcing deals with four pharmaceutical companies as well as the World Health Organization’s global vaccine project, known as COVAX.
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India must vaccinate 1.3bn people against Covid-19 – twice and twice as fast. With more than 9 million confirmed cases of coronavirus and a battered economy, how will the country meet this challenge?
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Grandmother-of-four Margaret Keenan, 90, has become the first person in the world to receive the shot as part of a vaccination programme.
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China's Sinovac Biotech SVA.O has secured $515 million in funding from a local firm to double production capacity of its coronavirus vaccine, the companies said on Monday, as it expects efficacy data of its experimental shot this month.
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The World Health Organization is holding discussions on Monday about the feasibility of trials in which healthy young volunteers are deliberately infected with coronavirus to hasten vaccine development – amid questions over whether they should go ahead given the promising data from the frontrunner vaccine candidates.
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Indonesia on Sunday received its first shipment of coronavirus vaccine from China, its president announced. "I want to convey the good news that today the government has received 1.2 million doses from China’s Sinovac Biotech Ltd." Joko Widodo told an online news briefing.
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Serum Institute of India, the world's largest vaccine maker by number of doses produced, has sought government approval for emergency use authorisation of the coronavirus vaccine that it is developing with the University of Oxford and British drugmaker AstraZeneca.
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With more than 100 vaccines currently in various trial phases and some reaching the pre-approval stage or being authorized for emergency use, accurate science reporting has never been more important. Journalists play a vital role in informing the public on science, specifically vaccine, developments, in an unprecedented period of scientific
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Britain's Queen Elizabeth II will receive the Pfizer-BioNTech coronavirus vaccine within weeks, after UK regulators granted emergency approval and the world's first roll-out begins next week, reports late Saturday said.
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Recently, AstraZeneca announced its vaccine is about 70 percent effective at preventing COVID-19. But a closer look at the clinical trials shows the efficacy isn’t as clear-cut as the pharmaceutical initially stated. Here’s what experts make of AstraZeneca’s vaccine trials.
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After Wall Street Journal claiming Pfizer and BioNTech suddenly scaled back distribution targets for their mRNA-based coronavirus vaccine in 2020, the drugmaker said those revised plans were nothing new and, in fact, had been laid out last month.
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Western vaccine makers appear to have taken the lead in the global race to produce a vaccine, but Chinese vaccine makers may help fill in the gaps they leave behind.
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In the US, COVID-19 vaccines are just around the corner, leaving the entire country peering out the window in anticipation of their arrival. Officials and healthcare systems, already taxed by skyrocketing case counts are making sure that everything is prepared when they show up
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Moderna will be able to produce 500 million doses of its COVID-19 vaccine in 2021, Chief Executive Officer Stéphane Bancel said on Friday
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China will have 600 million doses of Covid-19 vaccines ready for market this year and will make “a major announcement” soon, a scientist in charge of vaccine development said on Friday.
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Bahrain announced on Friday that it had approved the emergency use of the Pfizer-BioNTech coronavirus vaccine, becoming the second country after Britain to green-light the drug.
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When the pandemic began, rich countries went on a buying spree. Some have even called it "panic buying." These countries started making agreements with pharmaceutical companies to purchase experimental COVID-19 vaccines, even before clinical trials had finished.
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Covid-19 vaccine side-effects that range from fevers and chills to headaches and joint pain could keep some doctors and nurses from working amid a nationwide surge in hospitalizations.
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while people in Europe and the United States can expect the vaccines to become available soon, Chinese drug companies have yet to present their trial data even though the country was among those leading the way in the early phases of the research process.
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Former Presidents Barack Obama, George W. Bush, and Bill Clinton are volunteering to get their COVID-19 vaccines on camera as soon as the US Food and Drug Administration authorizes one for public use.
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Vaccines that prevent symptomatic Covid infection in roughly 95% of people vaccinated should, over time, help the world return to a normal life. But if we’re not careful, we could fail to take full advantage of the opportunity scientists and governments, pharmaceutical companies and philanthropic foundations have created for us.
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The forthcoming vaccines for COVID-19, even though they've been developed in record time, will meet similar standards for safety and effectiveness, according to infectious disease experts, immunologists, and bioethicists who spoke with Mashable.
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Considering worldwide need for a vaccine, there is room for many players. As of Dec. 1, 11 coronavirus vaccine developers have moved their projects into phase 3 clinical trials. Of those 11, five are companies based in the U.S. or Europe. We need all five of these companies -- and
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Russian President Vladimir Putin has ordered mass immunization against COVID-19 as Russia races to reverse a surge in coronavirus cases and be the first in the world to distribute its vaccine widely.
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The UK has approved a COVID-19 vaccine and plans to implement the treatment as early as next week. British care home residents, older adults and health care workers will be first to be inoculated with the groundbreaking vaccine developed by Pfizer and BioNTech to tackle the coronavirus pandemic.
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France hopes to offer Covid-19 vaccinations to the general public between April and June next year, President Emmanuel Macron told a press briefing at the Élysée Palace on Tuesday. Early 2021 will see a first campaign targeting those most at risk followed by a second campaign for the rest of
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